BGI Adopts Single Molecule, Real-Time Sequencing from Pacific Biosciences

PacBio RS II Systems to Be Used for Projects Such As De Novo Genome Assembly, Whole-Genome Methylation Analysis and Transcript Isoform Characterization

MENLO PARK, Calif., –  Pacific Biosciences of California, Inc., (Nasdaq:PACB) provider of the PacBio® RS II Sequencing System, today announced that BGI, the world’s largest genomics organization, has purchased its first PacBio RS II instrument and plans to purchase additional units in order to integrate Single Molecule, Real-Time (SMRT®) Sequencing into its global service business.

“The de novo genome services offered by BGI will be supported by SMRT sequencing technology to take advantage of its long reads and improved accuracy of assembly,” said Dr. Wang Jun, CEO of BGI. “The PacBio platform is ideal for complex genomes, such as those that are highly repetitive or hybrid. With the PacBio RS II we expect to meet our goal of delivering only complete genomes to our customers, and providing the best possible reference genomes for plants, animals and humans.”

The PacBio RS II delivers the industry’s longest read lengths combined with unbiased coverage and high accuracy. These characteristics enable customers to access the complete spectrum of sequence variant types, from single nucleotide polymorphisms to complex structural variation, and from genomic regions that were previously inaccessible. In addition, SMRT Sequencing is the only technology that provides direct detection of base modifications and direct variant phasing information across full-length genes and chromosome haplotype blocks.

Michael Hunkapiller, President and CEO of Pacific Biosciences, commented, “It’s a great validation to us that the world’s leading and largest sequencing operation has adopted PacBio technology. BGI is also a leader in sequencing data analysis, so we are delighted that more SMRT Sequencing data will be in their hands to work with and hopefully develop additional tools to help realize the full value of the data.”

About Pacific Biosciences   

Pacific Biosciences of California, Inc. (NASDAQ: PACB) offers the PacBio® RS II Sequencing System to help scientists resolve genetically complex problems. Based on its novel Single Molecule, Real-Time (SMRT®) technology, the company’s products enable: de novo genome assembly to finish genomes in order to more fully identify, annotate and decipher genomic structures; full-length transcript analysis to improve annotations in reference genomes, characterize alternatively spliced isoforms in important gene families, and find novel genes; targeted sequencing to more comprehensively characterize genetic variations; and DNA base modification identification to help characterize epigenetic regulation and DNA damage. Our technology provides the industry’s highest consensus accuracy over the longest read lengths in combination with the ability to detect real-time kinetic information. The PacBio RS II System, including consumables and software, provides a simple, fast, end-to-end workflow for SMRT Sequencing. More information is available at

About BGI

BGI was founded in 1999 with the mission of being a premier scientific partner to the global research community. The goal of BGI is to make leading-edge genomic science highly accessible through its investment in infrastructure that leverages the best available technology, economies of scale, and expert bioinformatics resources. BGI, which includes both private non-profit genomic research institutes and sequencing application commercial units, and its affiliates, BGI Americas, and BGI Europe, have established partnerships and collaborations with leading academic and government research institutions as well as global biotechnology and pharmaceutical companies, supporting a variety of disease, agricultural, environmental, and related applications. BGI has achieved a proven track record of excellence, delivering results with high efficiency and accuracy for innovative, high-profile research which has generated over 600 publications in top-tier scientific journals. BGI Tech Solutions Company, a subsidiary of BGI, provides sequencing and bioinformatics service solutions for global biomedical, agricultural, and environmental customers.

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Forward Looking Statements

All statements in this press release that are not historical are forward-looking statements, including, among other things, statements relating to purchase commitments, future uses and performance of the Company’s products and other future events. You should not place undue reliance on forward-looking statements because they involve known and unknown risks, uncertainties and other factors that are, in some cases, beyond the Company’s control and could materially affect actual results. Factors that could materially affect actual results can be found in our most recent filings with the Securities and Exchange Commission, including our most recent reports on Forms 8-K, 10-K, and 10-Q, and include those listed under the caption “Risk Factors.” The Company undertakes no obligation to update forward-looking statements.


For Pacific Biosciences:

Media:                                                            Investors:
Nicole Litchfield                                            Trevin Rard
415.793.6468                                                650.521.8450
[email protected]                                 [email protected]

For BGI:

Bicheng Yang Ph.D.
[email protected]

Joyce Peng, Ph.D.
Marketing Director
BGI Tech & BGI America
[email protected]