| Huan Gao Bioinformatics Engineer, BGI-Tech Sub Topic:
PDXomics Solution at BGI: Accelerate Your Cancer Research and Drug Discovery Abstract:
Empowered by world-class supercomputing platforms, state-of-the-art analysis tools and experienced bioinformaticans, BGI delivers industry-leading bioinformatics solutions for NGS data analysis. This seminar will provide a high level overview of the bioinformatics pipelines provided by BGI. In addition, we will introduce a novel, advanced bioinformatics solution, PDXomics, for tumor xenograft research. The solution enables the prediction of somatic mutations without the presence of normal tissues, provides a more efficient method for filtering out the mouse genome contamination, and enhances the validation of genetic variants using our comprehensive cancer genome databases. |
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| Jeremy Bruestle CTO, Spiral Genetics Sub Topic:
Anchored Assembly: Comprehensive Variant Detection Using NGS Data Abstract:
Anchored Assembly is a novel method for detecting all forms of genetic changes, from SNPs and small indels to large structural changes, using existing NGS data. The method accurately detects over 95% of large structural variations up to 56 kb and 99% of SNPs, with a low false positive rate. |
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| Sebastian Wernicke, Ph.D. Director, Seven Bridges Genomics Sub Topic:
Secure, Accurate, Scalable: NGS Analysis with Seven Bridges Abstract:
Seven Bridges believes that developing and scaling NGS data analysis requires more than raw computation and storage: Pipelines need to be scientifically sound and reproducible. Data security must go beyond “meeting the standards”. And developers need easy access to develop and automate. |
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| Nathan Pearson, Ph.D. Principal Genome Scientist, QIAGEN’s Center of Excellence in Biological Interpretation Sub Topic:
Understanding Myopia Using QIAGEN’s Powerful Ingenuity® Tools to Analyze and Interpret Whole Genome Data Abstract:
QIAGEN’s Ingenuity Variant Analysis provides researchers a powerful web-based platform for identifying and interpreting variants derived from DNA sequencing data. Dr. Pearson will discuss a recent myopia cohort study of whole genome sequencing data from more than 100 people shared through Harvard University’s Personal Genome Project (PGP). |
